6H0M
17beta-hydroxysteroid dehydrogenase type 14 mutant K158A in complex with Nicotinamide Adenine Dinucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 17-beta-hydroxysteroid dehydrogenase 14 | polymer | 270 | 28271.3 | 1 | UniProt (Q9BPX1) Pfam (PF13561) In PDB | Homo sapiens (Human) | 17-beta-HSD 14,17-beta-hydroxysteroid dehydrogenase DHRS10,Dehydrogenase/reductase SDR family member 10,Retinal short-chain dehydrogenase/reductase retSDR3,Short chain dehydrogenase/reductase family 47C member 1 |
| 2 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 3 | A | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 4 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | A | beta-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (BGC) | |||
| 6 | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A: 1 - 270 (UniProt: Q9BPX1)
| PDB | External Database | Details |
|---|---|---|
| Ala 158 | Lys 158 | engineered mutation |
| Ser 205 | Thr 205 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28271.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 944.7 | |
| All* | Total formula weight | 29216.0 |
