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6GYN

Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4polymer52160836.84UniProt (Q9Y3Q4)
Pfam (PF08412)
Pfam (PF00520)
Pfam (PF00027)
Homo sapiens (Human)
2AA, DA, E, EA, F...
(C, A, D, B)
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer790.128Chemie (PC1)
3BA, CA, H, I, MA...
(C, A, D, B)
1,2-Distearoyl-sn-glycerophosphoethanolaminenon-polymer748.18Chemie (3PE)
Sequence modifications
A, B, C, D: 201 - 719 (UniProt: Q9Y3Q4)
PDBExternal DatabaseDetails
Ser 199-expression tag
Met 200-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight243347.0
Non-Polymers*Number of molecules36
Total formula weight28108.6
All*Total formula weight271455.6
*Water molecules are not included.

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PDB entries from 2025-10-29

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