6GX2
Blood group synthase AAGlyB in complex with UDP-GalNAc and cryoprotected with glycerol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) | polymer | 298 | 34654.0 | 1 | UniProt (F0X360) Pfam (PF03414) UniProt (by SIFTS) (P16442) | Homo sapiens (Human) | |
| 2 | B (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | C (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | I, J (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | K (A) | water | water | 18.0 | 413 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: F0X360)
| PDB | External Database | Details |
|---|---|---|
| Met 57 | - | initiating methionine |
| Ala 58 | - | expression tag |
| Ile 59 | - | expression tag |
| Gly 60 | - | expression tag |
| Glu 61 | - | expression tag |
| Phe 62 | - | expression tag |
| Met 63 | - | expression tag |
| Gly 266 | Leu 256 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34654.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1021.6 | |
| All* | Total formula weight | 35675.6 |
