6GWG
Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of galactose covalently linked to the nucleophile
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-galactosidase | polymer | 575 | 66198.1 | 1 | UniProt (G4FEF4) Pfam (PF22676) Pfam (PF02065) | Thermotoga maritima MSB8 | Melibiase |
| 2 | B, C, D, E, F... (A) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | J (A) | (1~{S},2~{S},3~{S})-3-fluoranyl-6-(hydroxymethyl)cyclohex-5-ene-1,2,4-triol | non-polymer | 178.2 | 1 | Chemie (FEK) | |||
| 4 | K, L, M (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | N, O (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | P (A) | water | water | 18.0 | 470 | Chemie (HOH) |
Sequence modifications
A: 1 - 552 (UniProt: G4FEF4)
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| Gly -21 | - | expression tag |
| Ser -20 | - | expression tag |
| Ser -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Ser -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Val -8 | - | expression tag |
| Pro -7 | - | expression tag |
| Arg -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| His -3 | - | expression tag |
| Met -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66198.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1203.8 | |
| All* | Total formula weight | 67401.9 |
