6GVS
Engineered glycolyl-CoA reductase comprising 8 mutations with bound NADP+
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Aldehyde dehydrogenase | polymer | 522 | 55275.1 | 10 | UniProt (Q21A49) Pfam (PF00171) In PDB | Rhodopseudomonas palustris BisB18 | |
2 | I, J, A, B, C... | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 10 | Chemie (NAP) | Rhodopseudomonas palustris BisB18 | ||
3 | I, J, A, B, C... | POTASSIUM ION | non-polymer | 39.1 | 10 | Chemie (K) | |||
4 | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 59 - 522 (UniProt: Q21A49)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Ala 2 | - | expression tag |
His 3 | - | expression tag |
His 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
Val 9 | - | expression tag |
Gly 10 | - | expression tag |
Thr 11 | - | expression tag |
Asn 12 | - | expression tag |
Asp 13 | - | expression tag |
Ala 14 | - | expression tag |
Asn 15 | - | expression tag |
Ile 16 | - | expression tag |
Ala 17 | - | expression tag |
Asp 18 | - | expression tag |
Val 19 | - | expression tag |
Val 20 | - | expression tag |
Thr 21 | - | expression tag |
Lys 22 | - | expression tag |
Val 23 | - | expression tag |
Leu 24 | - | expression tag |
Gly 25 | - | expression tag |
Glu 26 | - | expression tag |
Tyr 27 | - | expression tag |
Gly 28 | - | expression tag |
Ala 29 | - | expression tag |
Pro 30 | - | expression tag |
Gly 31 | - | expression tag |
Ala 32 | - | expression tag |
Val 33 | - | expression tag |
Ser 34 | - | expression tag |
Val 35 | - | expression tag |
Ala 36 | - | expression tag |
Ala 37 | - | expression tag |
Leu 38 | - | expression tag |
Thr 39 | - | expression tag |
Ala 40 | - | expression tag |
Lys 41 | - | expression tag |
Ser 42 | - | expression tag |
Pro 43 | - | expression tag |
Asp 44 | - | expression tag |
Gly 45 | - | expression tag |
Lys 46 | - | expression tag |
Ser 47 | - | expression tag |
Asn 48 | - | expression tag |
Ser 49 | - | expression tag |
Ser 50 | - | expression tag |
Ala 51 | - | expression tag |
Asp 52 | - | expression tag |
Ala 53 | - | expression tag |
Asp 54 | - | expression tag |
Val 55 | - | expression tag |
Val 56 | - | expression tag |
Ala 57 | - | expression tag |
Arg 58 | - | expression tag |
Gly 222 | Pro 164 | engineered mutation |
Arg 257 | Ile 199 | engineered mutation |
Leu 261 | Asn 203 | engineered mutation |
Leu 280 | Ile 222 | engineered mutation |
Ile 326 | Leu 268 | engineered mutation |
Thr 327 | Pro 269 | engineered mutation |
Thr 329 | Val 271 | engineered mutation |
His 481 | Leu 423 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 552751.4 | |
Non-Polymers* | Number of molecules | 20 |
Total formula weight | 7825.0 | |
All* | Total formula weight | 560576.4 |