6GVS
Engineered glycolyl-CoA reductase comprising 8 mutations with bound NADP+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Aldehyde dehydrogenase | polymer | 522 | 55275.1 | 10 | UniProt (Q21A49) Pfam (PF00171) | Rhodopseudomonas palustris BisB18 | |
| 2 | AA, CA, K, M, O... (I, J, A, B, C...) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 10 | Chemie (NAP) | Rhodopseudomonas palustris BisB18 | ||
| 3 | BA, DA, L, N, P... (I, J, A, B, C...) | POTASSIUM ION | non-polymer | 39.1 | 10 | Chemie (K) | |||
| 4 | EA, FA, GA, HA, IA... (A, B, C, D, E...) | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 59 - 522 (UniProt: Q21A49)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| Val 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Thr 11 | - | expression tag |
| Asn 12 | - | expression tag |
| Asp 13 | - | expression tag |
| Ala 14 | - | expression tag |
| Asn 15 | - | expression tag |
| Ile 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Asp 18 | - | expression tag |
| Val 19 | - | expression tag |
| Val 20 | - | expression tag |
| Thr 21 | - | expression tag |
| Lys 22 | - | expression tag |
| Val 23 | - | expression tag |
| Leu 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Glu 26 | - | expression tag |
| Tyr 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Ala 29 | - | expression tag |
| Pro 30 | - | expression tag |
| Gly 31 | - | expression tag |
| Ala 32 | - | expression tag |
| Val 33 | - | expression tag |
| Ser 34 | - | expression tag |
| Val 35 | - | expression tag |
| Ala 36 | - | expression tag |
| Ala 37 | - | expression tag |
| Leu 38 | - | expression tag |
| Thr 39 | - | expression tag |
| Ala 40 | - | expression tag |
| Lys 41 | - | expression tag |
| Ser 42 | - | expression tag |
| Pro 43 | - | expression tag |
| Asp 44 | - | expression tag |
| Gly 45 | - | expression tag |
| Lys 46 | - | expression tag |
| Ser 47 | - | expression tag |
| Asn 48 | - | expression tag |
| Ser 49 | - | expression tag |
| Ser 50 | - | expression tag |
| Ala 51 | - | expression tag |
| Asp 52 | - | expression tag |
| Ala 53 | - | expression tag |
| Asp 54 | - | expression tag |
| Val 55 | - | expression tag |
| Val 56 | - | expression tag |
| Ala 57 | - | expression tag |
| Arg 58 | - | expression tag |
| Gly 222 | Pro 164 | engineered mutation |
| Arg 257 | Ile 199 | engineered mutation |
| Leu 261 | Asn 203 | engineered mutation |
| Leu 280 | Ile 222 | engineered mutation |
| Ile 326 | Leu 268 | engineered mutation |
| Thr 327 | Pro 269 | engineered mutation |
| Thr 329 | Val 271 | engineered mutation |
| His 481 | Leu 423 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 552751.4 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 7825.0 | |
| All* | Total formula weight | 560576.4 |
