6GR2

Structure of human galactokinase in complex with galactose and ADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Galactokinase	polymer	399	43103.0	8	UniProt (P51570) Pfam (PF10509) Pfam (PF00288) Pfam (PF08544) In PDB	Homo sapiens (Human)	Galactose kinase
2	H, A, B, C, D...	beta-D-galactopyranose	non-polymer		180.2	8	Chemie (GAL)
3	H, A, B, C, D...	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	8	Chemie (ADP)
4	H, B, C, F	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
5		water	water		18.0	103	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 2 - 392 (UniProt: P51570)

PDB	External Database	Details
Met -6	-	initiating methionine
Ala -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Ala 252	Lys 252	conflict
Ala 253	Glu 253	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	344823.8
Non-Polymers*	Number of molecules	21
	Total formula weight	5339.2
All*	Total formula weight	350163.0

*Water molecules are not included.