6GJS
Human NBD1 of CFTR in complex with nanobodies D12 and T4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cystic fibrosis transmembrane conductance regulator | polymer | 229 | 25525.4 | 1 | UniProt (Q20BJ8) Pfam (PF00005) UniProt (by SIFTS) (P13569) | Homo sapiens (Human) | ATP-binding cassette sub-family C member 7,Channel conductance-controlling ATPase,cAMP-dependent chloride channel |
| 2 | B (B) | Nanobody D12 | polymer | 149 | 16273.9 | 1 | Lama glama (llama) | ||
| 3 | C (C) | Nanobody T4 | polymer | 143 | 15488.1 | 1 | Lama glama (llama) | ||
| 4 | D, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | E (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 6 | G, H, I (A, B, C) | water | water | 18.0 | 426 | Chemie (HOH) |
Sequence modifications
A: 387 - 646 (UniProt: Q20BJ8)
| PDB | External Database | Details |
|---|---|---|
| Ser 386 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 57287.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 555.8 | |
| All* | Total formula weight | 57843.2 |
