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6GID

High resolution crystal structure of substrate-free human neprilysin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Neprilysinpolymer69679525.51UniProt (P08473)
Pfam (PF05649)
Pfam (PF01431)
Homo sapiens (Human)Atriopeptidase,Common acute lymphocytic leukemia antigen,CALLA,Enkephalinase,Neutral endopeptidase 24.11,Neutral endopeptidase,Skin fibroblast elastase,SFE
2B, C, D, E
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
3F
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4G, H, I, J, K...
(A)
1,2-ETHANEDIOLnon-polymer62.16Chemie (EDO)
5M, N
(A)
NITRATE IONnon-polymer62.02Chemie (NO3)
6O, P, Q
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.13Chemie (PEG)
7R
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
8S
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
9T
(A)
waterwater18.0463Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight79525.5
Non-Polymers*Number of molecules18
Total formula weight1952.1
All*Total formula weight81477.6
*Water molecules are not included.

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PDB entries from 2026-02-25

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