6GH8
Crystal structure of GP1 domain of Lujo virus in complex with the first CUB domain of neuropilin-2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D, B | Glycoprotein | polymer | 139 | 16021.9 | 2 | UniProt (C5ILC1) Pfam (PF00798) In PDB | Lujo mammarenavirus | |
2 | A, C | Neuropilin-2 | polymer | 133 | 14914.5 | 2 | UniProt (O60462) Pfam (PF00431) In PDB | Homo sapiens (Human) | Vascular endothelial cell growth factor 165 receptor 2 |
3 | D, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
4 | A, C | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
5 | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
D, B: 74 - 199 (UniProt: C5ILC1)
A, C: 27 - 146 (UniProt: O60462)
PDB | External Database | Details |
---|---|---|
Ala 61 | - | expression tag |
Asp 62 | - | expression tag |
Leu 63 | - | expression tag |
Gly 64 | - | expression tag |
Ser 65 | - | expression tag |
His 66 | - | expression tag |
His 67 | - | expression tag |
His 68 | - | expression tag |
His 69 | - | expression tag |
His 70 | - | expression tag |
His 71 | - | expression tag |
Gly 72 | - | expression tag |
Gly 73 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 22 | - | expression tag |
Asp 23 | - | expression tag |
Leu 24 | - | expression tag |
Gly 25 | - | expression tag |
Ser 26 | - | expression tag |
Arg 123 | Lys 123 | conflict |
Gly 147 | - | expression tag |
Thr 148 | - | expression tag |
His 149 | - | expression tag |
His 150 | - | expression tag |
His 151 | - | expression tag |
His 152 | - | expression tag |
His 153 | - | expression tag |
His 154 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 61872.8 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 743.8 | |
All* | Total formula weight | 62616.6 |