6GFE
High-resolution Structure of a therapeutic full-length anti-NPRA Antibody with exceptional Conformational Diversity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (H, K) | Immunoglobulin gamma-4 heavy chain | polymer | 450 | 49883.8 | 2 | Homo sapiens (Human) | ||
| 2 | C, D (L, M) | Immunoglobulin gamma-4 light chain | polymer | 215 | 23360.9 | 2 | Homo sapiens (Human) | ||
| 3 | E, F (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1260.2 | 2 | In PDB GlyTouCan (G45889JQ) | |||
| 4 | G, H (H, K) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | I, J, K (K, L) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 6 | L, M, N, O (H, K, L, M) | water | water | 18.0 | 1286 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 146489.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2520.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 257.3 | |
| All* | Total formula weight | 149267.0 |
