6GFE

High-resolution Structure of a therapeutic full-length anti-NPRA Antibody with exceptional Conformational Diversity

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H, K	Immunoglobulin gamma-4 heavy chain	polymer	450	49883.8	2		Homo sapiens (Human)
2	L, M	Immunoglobulin gamma-4 light chain	polymer	215	23360.9	2		Homo sapiens (Human)
3	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1260.2	2	In PDB GlyTouCan (G45889JQ)
4	H, K	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
5	K, L	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
6		water	water		18.0	1286	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	146489.4
Branched	Number of molecules	2
	Total formula weight	2520.3
Non-Polymers*	Number of molecules	5
	Total formula weight	257.3
All*	Total formula weight	149267.0

*Water molecules are not included.