6GEC
TEAD4 (216-434) COMPLEXED WITH YAP PEPTIDE (60-100);S94A AND MYRISTOATE (COVALENTLY BOUND) AT 1.70A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transcriptional enhancer factor TEF-3 | polymer | 219 | 25500.7 | 1 | UniProt (Q15561) Pfam (PF17725) In PDB | Homo sapiens (Human) | TEA domain family member 4,TEAD-4,Transcription factor 13-like 1,Transcription factor RTEF-1 |
2 | L | Transcriptional coactivator YAP1 | polymer | 41 | 4531.2 | 1 | UniProt (P46937) Pfam (PF15238) In PDB | Homo sapiens | Yes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog |
3 | A | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
4 | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
L: 60 - 99 (UniProt: P46937)
PDB | External Database | Details |
---|---|---|
Ace 59 | - | expression tag |
Ala 94 | Ser 94 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 30032.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 228.4 | |
All* | Total formula weight | 30260.3 |