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6GEC

TEAD4 (216-434) COMPLEXED WITH YAP PEPTIDE (60-100);S94A AND MYRISTOATE (COVALENTLY BOUND) AT 1.70A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATranscriptional enhancer factor TEF-3polymer21925500.71UniProt (Q15561)
Pfam (PF17725)
In PDB
Homo sapiens (Human)TEA domain family member 4,TEAD-4,Transcription factor 13-like 1,Transcription factor RTEF-1
2LTranscriptional coactivator YAP1polymer414531.21UniProt (P46937)
Pfam (PF15238)
In PDB
Homo sapiensYes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog
3AMYRISTIC ACIDnon-polymer228.41Chemie (MYR)
4waterwater18.0205Chemie (HOH)
Sequence modifications
L: 60 - 99 (UniProt: P46937)
PDBExternal DatabaseDetails
Ace 59-expression tag
Ala 94Ser 94engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight30032.0
Non-Polymers*Number of molecules1
Total formula weight228.4
All*Total formula weight30260.3
*Water molecules are not included.

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PDB entries from 2024-07-24

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