6GCS

Cryo-EM structure of respiratory complex I from Yarrowia lipolytica

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	75-KDA PROTEIN (NUAM)	polymer	728	79088.1	1	UniProt (Q9UUU3) Pfam (PF13510) Pfam (PF10588) Pfam (PF00384) Pfam (PF09326) In PDB	Yarrowia lipolytica
2	B	51-KDA PROTEIN (NUBM)	polymer	488	53829.5	1	UniProt (Q9UUU2) Pfam (PF01512) Pfam (PF10531) Pfam (PF10589) In PDB	Yarrowia lipolytica
3	C	49-KDA PROTEIN (NUCM)	polymer	466	52494.9	1	UniProt (Q9UUU1) Pfam (PF00346) In PDB	Yarrowia lipolytica
4	D	NIMM SUBUNIT	polymer	87	9806.2	1	UniProt (A0A1D8NC63) Pfam (PF15879) UniProt (by SIFTS) (B5FVD3) In PDB	Yarrowia lipolytica
5	E	NUEM SUBUNIT	polymer	375	42765.7	1	UniProt (Q6C7X4) Pfam (PF01370) In PDB	Yarrowia lipolytica
6	F	NUFM SUBUNIT	polymer	144	16657.9	1	UniProt (Q6C4W9) Pfam (PF04716) In PDB	Yarrowia lipolytica
7	G	30-KDA PROTEIN (NUGM)	polymer	281	32389.6	1	UniProt (Q9UUU0) Pfam (PF00329) In PDB	Yarrowia lipolytica
8	H	24-KDA SUBUNIT (NUHM)	polymer	243	27247.4	1	UniProt (Q9UUT9) Pfam (PF01257) In PDB	Yarrowia lipolytica
9	I	TYKY SUBUNIT (NUIM)	polymer	229	25682.3	1	UniProt (Q9UUT8) Pfam (PF12838) In PDB	Yarrowia lipolytica
10	J	NUJM SUBUNIT	polymer	198	20849.6	1	UniProt (Q6C674) In PDB	Yarrowia lipolytica
11	K	PSST SUBUNIT (NUKM)	polymer	210	23455.2	1	UniProt (Q9UUT7) Pfam (PF01058) In PDB	Yarrowia lipolytica
12	L	ND4L SUBUNIT (NULM)	polymer	86	9482.5	1	UniProt (Q9B6D4) Pfam (PF00420) In PDB	Yarrowia lipolytica
13	M	NUMM SUBUNIT	polymer	136	15149.0	1	UniProt (A0A1H6Q8Z5) Pfam (PF10276) UniProt (by SIFTS) (Q6C8J9) In PDB	Yarrowia lipolytica
14	O	ACPM1 SUBUNIT	polymer	109	12053.6	1	UniProt (A0A1H6PXT9) Pfam (PF00550) UniProt (by SIFTS) (Q6C926) In PDB	Yarrowia lipolytica
15	P	NB4M SUBUNIT	polymer	124	14778.8	1	UniProt (A0A1D8N3C8) Pfam (PF13233) UniProt (by SIFTS) (Q6CI60) In PDB	Yarrowia lipolytica
16	Q	ACPM2 SUBUNIT	polymer	132	14444.5	1	UniProt (A0A1D8NG21) Pfam (PF00550) UniProt (by SIFTS) (Q6C7X2) In PDB	Yarrowia lipolytica
17	R	NI2M SUBUNIT	polymer	109	12902.9	1	UniProt (A0A1D8NDL1) UniProt (by SIFTS) (Q6C9Z1) In PDB	Yarrowia lipolytica
18	S	NESM SUBUNIT	polymer	159	13549.7	1		Yarrowia lipolytica
19	U	NUPM SUBUNIT	polymer	172	19355.2	1	UniProt (Q6CGB4) Pfam (PF06747) In PDB	Yarrowia lipolytica
20	W	NB6M SUBUNIT	polymer	123	14112.4	1	UniProt (A0A1H6PPE5) Pfam (PF06212) UniProt (by SIFTS) (B5FVF8) In PDB	Yarrowia lipolytica
21	X	NUXM SUBUNIT	polymer	169	18588.2	1	UniProt (A0A1D8NKB4) Pfam (PF10785) Pfam (PF12853) UniProt (by SIFTS) (Q6C4A6) In PDB	Yarrowia lipolytica
22	Y	NUYM SUBUNIT	polymer	161	18656.1	1	UniProt (A0A1D8N7X0) Pfam (PF04800) UniProt (by SIFTS) (Q6CEK9) In PDB	Yarrowia lipolytica
23	Z	NUZM SUBUNIT	polymer	137	11677.4	1		Yarrowia lipolytica
24	a	NIAM SUBUNIT	polymer	100	8528.5	1		Yarrowia lipolytica
25	b	NEBM SUBUNIT	polymer	64	5464.7	1		Yarrowia lipolytica
26	c	NB2M SUBUNIT	polymer	60	6948.9	1	UniProt (B5FVE5) Pfam (PF08122) In PDB	Yarrowia lipolytica
27	d	NIDM SUBUNIT	polymer	92	11039.3	1	UniProt (A0A1D8N596) Pfam (PF10249) UniProt (by SIFTS) (B5RSK3) In PDB	Yarrowia lipolytica
28	e	NUUM SUBUNIT	polymer	45	3847.7	1		Yarrowia lipolytica
29	f	NI8M SUBUNIT	polymer	87	9621.1	1	UniProt (A0A1H6PJS3) Pfam (PF05047) UniProt (by SIFTS) (Q6CD73) In PDB	Yarrowia lipolytica
30	g	NI9M SUBUNIT	polymer	63	7233.3	1	UniProt (A0A1D8NJR0) UniProt (by SIFTS) (B5FVF3) In PDB	Yarrowia lipolytica
31	h	N7BM SUBUNIT	polymer	138	16175.1	1	UniProt (Q6CG53) Pfam (PF05071) In PDB	Yarrowia lipolytica
32	i	UNKNOWN SUBUNIT	polymer	53	4528.6	1		Yarrowia lipolytica
33	j	NB5M SUBUNIT	polymer	93	10494.9	1	UniProt (Q6ZY24) In PDB	Yarrowia lipolytica
34	n	NUNM SUBUNIT	polymer	93	7932.8	1		Yarrowia lipolytica
35	1	ND1 SUBUNIT (NU1M)	polymer	341	38361.3	1	UniProt (Q9B6E8) Pfam (PF00146) In PDB	Yarrowia lipolytica	NADH dehydrogenase subunit 1
36	2	ND2 SUBUNIT (NU2M)	polymer	469	53353.4	1	UniProt (Q9B6C8) Pfam (PF00361) In PDB	Yarrowia lipolytica	NADH dehydrogenase subunit 2
37	3	ND3 SUBUNIT (NU3M)	polymer	128	14478.3	1	UniProt (Q9B6C7) Pfam (PF00507) In PDB	Yarrowia lipolytica	NADH dehydrogenase subunit 3
38	4	ND4 SUBUNIT (NU4M)	polymer	486	54506.6	1	UniProt (Q9B6D6) Pfam (PF00361) In PDB	Yarrowia lipolytica	NADH dehydrogenase subunit 4
39	5	ND5 SUBUNIT (NU5M)	polymer	655	73740.7	1	UniProt (Q9B6D3) Pfam (PF00662) Pfam (PF00361) In PDB	Yarrowia lipolytica	NADH dehydrogenase subunit 5
40	6	ND6 SUBUNIT (NU6M)	polymer	185	20765.1	1	UniProt (Q9B6E9) Pfam (PF00499) In PDB	Yarrowia lipolytica	NADH dehydrogenase subunit 6
41	8	NB8M SUBUNIT	polymer	99	11219.0	1	UniProt (A0A1H6PKH9) Pfam (PF05676) UniProt (by SIFTS) (B5FVG1) In PDB	Yarrowia lipolytica
42	9	NIPM SUBUNIT	polymer	89	10035.7	1	UniProt (A0A1D8NNZ0) Pfam (PF10200) UniProt (by SIFTS) (B5RSL7) In PDB	Yarrowia lipolytica
43	A, B, I, K	IRON/SULFUR CLUSTER	non-polymer		351.6	6	Chemie (SF4)
44	A, H	FE2/S2 (INORGANIC) CLUSTER	non-polymer		175.8	2	Chemie (FES)
45	B	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	1	Chemie (FMN)
46	E	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	1	Chemie (NDP)
47	M	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
48	O	S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate	non-polymer		568.7	1	Chemie (ZMP)
49	g	CARDIOLIPIN	non-polymer		1464.0	1	Chemie (CDL)
50	g, 1, 4	1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE	non-polymer		748.1	3	Chemie (3PE)

Contents of the asymmetric unit

Polymers	Number of chains	42
	Total formula weight	927291.5
Non-Polymers*	Number of molecules	16
	Total formula weight	8005.6
All*	Total formula weight	935297.1

*Water molecules are not included.