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6GCR

Focal Adhesion Kinase catalytic domain in complex with irreversible inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Focal adhesion kinase 1polymer27631731.81UniProt (Q00944)
Pfam (PF07714)
Gallus gallus (Chicken)FADK 1,Focal adhesion kinase-related nonkinase,p41/p43FRNK,Protein-tyrosine kinase 2,p125FAK,pp125FAK
2B
(A)
2-[[2-[[4-[[[3,4-bis(oxidanylidene)-2-[2-(propanoylamino)ethylamino]cyclobuten-1-yl]amino]methyl]phenyl]amino]-5-chloranyl-pyrimidin-4-yl]amino]-~{N}-methyl-benzamidenon-polymer577.01Chemie (EUW)
3C
(A)
waterwater18.066Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31731.8
Non-Polymers*Number of molecules1
Total formula weight577.0
All*Total formula weight32308.8
*Water molecules are not included.

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PDB entries from 2024-10-30

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