6GB2
Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the 39S ribosomal subunit.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (CL, DL, EL, FL, GL...) | Mitochondrial ribosomal protein L12 | polymer | 198 | 21269.0 | 7 | UniProt (A0A287ARV8) Pfam (PF16320) Pfam (PF00542) UniProt (by SIFTS) (A0A4X1U6S6) | Sus scrofa (Pig) | |
| 2 | G (B0) | Mitochondrial ribosomal protein L27 | polymer | 148 | 15943.7 | 1 | UniProt (F1RT79) Pfam (PF01016) UniProt (by SIFTS) (A0A4X1U0F6) | Sus scrofa (Pig) | |
| 3 | H (B1) | Mitochondrial ribosomal protein L28 | polymer | 256 | 30149.0 | 1 | UniProt (A0A286ZTW8) Pfam (PF00830) | Sus scrofa (Pig) | |
| 4 | I (B2) | Mitochondrial ribosomal protein L47 | polymer | 252 | 30085.1 | 1 | UniProt (F1SGC7) Pfam (PF06984) | Sus scrofa (Pig) | |
| 5 | J (B3) | 'Mitochondrial ribosomal protein L30 | polymer | 161 | 18585.8 | 1 | UniProt (F1STE5) Pfam (PF00327) UniProt (by SIFTS) (A0A8D1MIP3) | Sus scrofa (Pig) | |
| 6 | K (B4) | 'Mitochondrial ribosomal protein L55 | polymer | 126 | 15156.5 | 1 | UniProt (I3L9J0) Pfam (PF09776) UniProt (by SIFTS) (A0A4X1ULI6) | Sus scrofa (Pig) | |
| 7 | L (B5) | Mitochondrial ribosomal protein L32 | polymer | 188 | 21537.9 | 1 | Sus scrofa (Pig) | bL32m | |
| 8 | M (B6) | Mitochondrial ribosomal protein L33 | polymer | 65 | 7508.1 | 1 | UniProt (A0A286ZU68) Pfam (PF00471) UniProt (by SIFTS) (A0A4X1TLP9) | Sus scrofa (Pig) | |
| 9 | N (B7) | Mitochondrial ribosomal protein L34 | polymer | 95 | 10871.7 | 1 | UniProt (A0A287A119) Pfam (PF00468) UniProt (by SIFTS) (A0A4X1UFR4) | Sus scrofa (Pig) | |
| 10 | O (B8) | Mitochondrial ribosomal protein L35 | polymer | 188 | 21548.5 | 1 | UniProt (F1SVC5) | Sus scrofa (Pig) | |
| 11 | P (B9) | Ribosomal protein | polymer | 100 | 10841.0 | 1 | UniProt (A0A287A731) Pfam (PF00444) | Sus scrofa (Pig) | |
| 12 | Q (BA) | 16S ribosomal RNA, mitochondrial | polymer | 1571 | 504852.0 | 1 | GenBank (33320725) | Sus scrofa | |
| 13 | R (BB) | CP tRNAPhe, mitochondrial | polymer | 73 | 23402.0 | 1 | GenBank (76262549) | Sus scrofa | |
| 14 | S (BC) | Translation initiation factor IF-2, mitochondrial | polymer | 657 | 72811.2 | 1 | UniProt (P46199) Pfam (PF22042) Pfam (PF11987) Pfam (PF00009) | Homo sapiens (Human) | IF2(mt) |
| 15 | T (BD) | Mitochondrial ribosomal protein L2 | polymer | 306 | 33270.9 | 1 | UniProt (F1RRN2) Pfam (PF00181) | Sus scrofa (Pig) | |
| 16 | U (BE) | ICT1 | polymer | 348 | 38427.2 | 1 | Sus scrofa (Pig) | Mitochondrial ribosomal protein L3 | |
| 17 | V (BF) | Mitochondrial ribosomal protein L4 | polymer | 294 | 33251.5 | 1 | UniProt (A0A287B9C4) Pfam (PF00573) | Sus scrofa (Pig) | |
| 18 | W (BI) | Mitochondrial ribosomal protein L9 | polymer | 268 | 30373.4 | 1 | UniProt (I3LR45) Pfam (PF01281) Pfam (PF22078) | Sus scrofa (Pig) | |
| 19 | X (BJ) | Mitochondrial ribosomal protein L10 | polymer | 262 | 29449.7 | 1 | UniProt (F1RWJ0) Pfam (PF00466) | Sus scrofa (Pig) | |
| 20 | Y (BK) | Mitochondrial ribosomal protein L11 | polymer | 192 | 20809.3 | 1 | UniProt (F1RU54) Pfam (PF00298) | Sus scrofa (Pig) | |
| 21 | AA (BN) | Mitochondrial ribosomal protein L13 | polymer | 178 | 20633.8 | 1 | Sus scrofa (Pig) | uL13m | |
| 22 | BA (BO) | Mitochondrial ribosomal protein L14 | polymer | 145 | 15955.6 | 1 | Sus scrofa (Pig) | uL14m | |
| 23 | CA (BP) | Mitochondrial ribosomal protein L15 | polymer | 296 | 33481.7 | 1 | UniProt (F1RSH0) | Sus scrofa (Pig) | |
| 24 | DA (BQ) | Mitochondrial ribosomal protein L16 | polymer | 251 | 28680.5 | 1 | UniProt (F1RI89) Pfam (PF00252) | Sus scrofa (Pig) | |
| 25 | EA (BR) | Mitochondrial ribosomal protein L17 | polymer | 169 | 19268.2 | 1 | UniProt (F1RMQ4) Pfam (PF01196) | Sus scrofa (Pig) | |
| 26 | FA (BS) | Mitochondrial ribosomal protein L18 | polymer | 180 | 20582.6 | 1 | UniProt (A0A286ZNK1) Pfam (PF00861) | Sus scrofa (Pig) | |
| 27 | GA (BT) | Mitochondrial ribosomal protein L19 | polymer | 292 | 33441.5 | 1 | Sus scrofa (Pig) | ||
| 28 | HA (BU) | Mitochondrial ribosomal protein L20 | polymer | 149 | 17554.8 | 1 | UniProt (A0A286ZU56) Pfam (PF00453) | Sus scrofa (Pig) | |
| 29 | IA (BV) | Mitochondrial ribosomal protein L21 | polymer | 209 | 23154.9 | 1 | UniProt (F1RY70) Pfam (PF00829) | Sus scrofa (Pig) | |
| 30 | JA (BW) | Mitochondrial ribosomal protein L22 | polymer | 210 | 24313.4 | 1 | UniProt (F1RQC9) Pfam (PF00237) UniProt (by SIFTS) (A0A4X1TXR4) | Sus scrofa (Pig) | |
| 31 | KA (BX) | Mitochondrial ribosomal protein L23 | polymer | 150 | 17643.2 | 1 | UniProt (A0A286ZZC6) | Sus scrofa (Pig) | |
| 32 | LA (BY) | Mitochondrial ribosomal protein L24 | polymer | 216 | 24893.5 | 1 | UniProt (F1RHJ1) Pfam (PF00467) Pfam (PF17136) | Sus scrofa (Pig) | |
| 33 | MA (Ba) | Mitochondrial ribosomal protein L37 | polymer | 423 | 47918.0 | 1 | UniProt (A0A287BIV6) Pfam (PF07147) | Sus scrofa (Pig) | |
| 34 | NA (Bb) | Mitochondrial ribosomal protein L38 | polymer | 380 | 44656.4 | 1 | UniProt (F1RW03) Pfam (PF01161) | Sus scrofa (Pig) | |
| 35 | OA (Bc) | Mitochondrial ribosomal protein L39 | polymer | 334 | 38523.4 | 1 | UniProt (F1SHP6) | Sus scrofa (Pig) | |
| 36 | PA (Bd) | Mitochondrial ribosomal protein L40 | polymer | 206 | 24075.7 | 1 | UniProt (A0A286ZP98) Pfam (PF09812) | Sus scrofa (Pig) | |
| 37 | QA (Be) | Mitochondrial ribosomal protein L41 | polymer | 135 | 15073.4 | 1 | UniProt (A0A287AWS0) Pfam (PF09809) UniProt (by SIFTS) (A0A8D1F1K9) | Sus scrofa (Pig) | |
| 38 | RA (Bf) | Mitochondrial ribosomal protein L42 | polymer | 142 | 16680.2 | 1 | UniProt (A0A287BQA1) Pfam (PF10210) | Sus scrofa (Pig) | |
| 39 | SA (Bg) | Mitochondrial ribosomal protein L43 | polymer | 159 | 17728.1 | 1 | UniProt (F1S8U4) Pfam (PF05047) | Sus scrofa (Pig) | |
| 40 | TA (Bh) | Mitochondrial ribosomal protein L44 | polymer | 332 | 37527.2 | 1 | UniProt (F1SR64) Pfam (PF22935) Pfam (PF22892) | Sus scrofa (Pig) | |
| 41 | UA (Bi) | Mitochondrial ribosomal protein L45 | polymer | 306 | 35331.8 | 1 | UniProt (I3LGM5) Pfam (PF04280) | Sus scrofa (Pig) | |
| 42 | VA (Bj) | Mitochondrial ribosomal protein L46 | polymer | 279 | 32216.0 | 1 | UniProt (F1SRT0) Pfam (PF11788) | Sus scrofa (Pig) | |
| 43 | WA (Bk) | Mitochondrial ribosomal protein L48 | polymer | 212 | 23749.5 | 1 | UniProt (F1SUS9) Pfam (PF00338) UniProt (by SIFTS) (A0A480J9Z6) | Sus scrofa (Pig) | |
| 44 | XA (Bl) | Mrpl34 | polymer | 166 | 18957.8 | 1 | UniProt (A0A0R4J8D6) Pfam (PF05046) | Sus scrofa (Pig) | |
| 45 | YA (Bm) | Mitochondrial ribosomal protein L50 | polymer | 159 | 18351.0 | 1 | UniProt (I3L9H6) Pfam (PF10501) | Sus scrofa (Pig) | |
| 46 | ZA (Bn) | Mitochondrial ribosomal protein L51 | polymer | 128 | 15249.0 | 1 | UniProt (A0A287BE26) Pfam (PF10244) UniProt (by SIFTS) (A0A8D1P1C8) | Sus scrofa (Pig) | |
| 47 | AB (Bo) | Mitochondrial ribosomal protein L52 | polymer | 124 | 13813.7 | 1 | UniProt (F1S9B7) Pfam (PF18699) | Sus scrofa (Pig) | |
| 48 | BB (Bp) | mL53, MRPL53 | polymer | 112 | 12015.7 | 1 | Sus scrofa (Pig) | ||
| 49 | CB (Bq) | Uncharacterized protein | polymer | 138 | 15957.4 | 1 | UniProt (I3LN63) Pfam (PF08561) | Sus scrofa (Pig) | |
| 50 | DB (Bt) | Mitochondrial ribosomal protein L57 | polymer | 102 | 12001.9 | 1 | UniProt (A0A287BP93) Pfam (PF14978) | Sus scrofa (Pig) | |
| 51 | EB (Bu) | Mitochondrial ribosomal protein L58 | polymer | 205 | 23545.9 | 1 | UniProt (A0A286ZJR2) Pfam (PF00472) | Sus scrofa (Pig) | |
| 52 | FB (Bv) | 'Mitochondrial ribosomal protein L59 | polymer | 222 | 25815.0 | 1 | UniProt (A0A286ZXA6) Pfam (PF10147) | Sus scrofa (Pig) | |
| 53 | GB (Bw) | mL65, MRPS30 | polymer | 433 | 49100.5 | 1 | Sus scrofa (Pig) | ||
| 54 | HB (Bx) | Mitochondrial ribosomal protein S18A | polymer | 196 | 22273.1 | 1 | UniProt (F1RRH6) Pfam (PF01084) | Sus scrofa (Pig) | |
| 55 | IB (Bz) | unassigned secondary structure elements | polymer | 82 | 5846.4 | 1 | Sus scrofa (Pig) | ||
| 56 | JB (AV) | P-site fMet-tRNAMet, mitochondrial | polymer | 71 | 22664.5 | 1 | GenBank (1208989970) | Homo sapiens | |
| 57 | AC, AD, AE, AF, AG... (BA, Bt, B3, BB, BC...) | MAGNESIUM ION | non-polymer | 24.3 | 216 | Chemie (MG) | |||
| 58 | LB, MB, SJ (B5, B9, BJ) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 59 | HJ, IJ (BA) | GUANOSINE-5'-MONOPHOSPHATE | non-polymer | 363.2 | 2 | Chemie (5GP) | |||
| 60 | JJ, WJ (BA, BR) | SPERMINE | non-polymer | 202.3 | 2 | Chemie (SPM) | |||
| 61 | MJ (BC) | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (GSP) | |||
| 62 | OJ (BC) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 63 | BK (AV) | N-FORMYLMETHIONINE | non-polymer | 177.2 | 1 | Chemie (FME) | |||
| 64 | CK (BC) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
BB: 1 - 71 (GenBank: 76262549)
BC: 78 - 727 (UniProt: P46199)
BQ: 1 - 251 (UniProt: F1RI89)
Bl: 1 - 166 (UniProt: A0A0R4J8D6)
AV: 1 - 68 (GenBank: 1208989970)
| PDB | External Database | Details |
|---|---|---|
| C 72 | - | insertion |
| A 73 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Ser 71 | - | expression tag |
| Gly 72 | - | expression tag |
| Gly 73 | - | expression tag |
| Ser 74 | - | expression tag |
| Gly 75 | - | expression tag |
| Ser 76 | - | expression tag |
| Gly 77 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| His 237 | Tyr 237 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 59 | Lys 59 | conflict |
| PDB | External Database | Details |
|---|---|---|
| C 69 | - | insertion |
| C 70 | - | insertion |
| A 71 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 62 |
| Total formula weight | 1986432.8 | |
| Non-Polymers* | Number of molecules | 226 |
| Total formula weight | 7316.7 | |
| All* | Total formula weight | 1993749.5 |
