6G9T

CRYSTAL STRUCTURE OF CMY-136 class C BETA-LACTAMASE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-lactamase	polymer	371	41252.9	2	UniProt (G3F7G9) Pfam (PF00144)	Escherichia coli	CMY-136 Beta-lactamase
2	C, D, E, I, J (A, B)	PHOSPHATE ION	non-polymer		95.0	5	Chemie (PO4)
3	F, K, L (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	G, H, M, N, O (A, B)	ISOPROPYL ALCOHOL	non-polymer		60.1	5	Chemie (IPA)
5	P, Q (A, B)	water	water		18.0	396	Chemie (HOH)

Sequence modifications

A, B: 1 - 361 (UniProt: G3F7G9)

PDB	External Database	Details
His 221	Tyr 240	engineered mutation
Phe 362	-	expression tag
Glu 363	-	expression tag
His 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag
His 369	-	expression tag
His 370	-	expression tag
His 371	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	82505.8
Non-Polymers*	Number of molecules	13
	Total formula weight	1051.6
All*	Total formula weight	83557.4

*Water molecules are not included.