6G6L

The crystal structures of Human MYC:MAX bHLHZip complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	Myc proto-oncogene protein	polymer	94	11501.2	4	UniProt (P01106) Pfam (PF00010) Pfam (PF02344) In PDB	Homo sapiens (Human)	Class E basic helix-loop-helix protein 39,bHLHe39,Proto-oncogene c-Myc,Transcription factor p64
2	B, D, F, H	Protein max	polymer	83	9909.2	4	UniProt (P61244) Pfam (PF00010) In PDB	Homo sapiens (Human)	Class D basic helix-loop-helix protein 4,bHLHd4,Myc-associated factor X
3	A, B, C, D, E...	SULFATE ION	non-polymer		96.1	14	Chemie (SO4)
4		water	water		18.0	480	Chemie (HOH)

Sequence modifications

A, C, E, G: 898 - 984 (UniProt: P01106)

PDB	External Database	Details
Met 891	-	initiating methionine
His 892	-	expression tag
His 893	-	expression tag
His 894	-	expression tag
His 895	-	expression tag
His 896	-	expression tag
His 897	-	expression tag

B, D, F, H: 201 - 282 (UniProt: P61244)

PDB	External Database	Details
Met 200	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	85641.4
Non-Polymers*	Number of molecules	14
	Total formula weight	1344.9
All*	Total formula weight	86986.3

*Water molecules are not included.