6G6L

The crystal structures of Human MYC:MAX bHLHZip complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0046983	molecular_function	protein dimerization activity
B	0046983	molecular_function	protein dimerization activity
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription
C	0046983	molecular_function	protein dimerization activity
D	0046983	molecular_function	protein dimerization activity
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0006355	biological_process	regulation of DNA-templated transcription
E	0046983	molecular_function	protein dimerization activity
F	0046983	molecular_function	protein dimerization activity
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0006355	biological_process	regulation of DNA-templated transcription
G	0046983	molecular_function	protein dimerization activity
H	0046983	molecular_function	protein dimerization activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SO4 A 1001

Chain	Residue
A	LYS939
A	HOH1109
B	ARG214
G	LYS936

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 1002

Chain	Residue
A	GLN912
A	ASN915
A	ARG919
A	HOH1101
D	HIS258

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 B 301

Chain	Residue
A	ARG913
B	SER238
B	ARG239
B	HOH402
B	HOH406

---

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 C 1001

Chain	Residue
B	ARG254
B	HIS258
C	GLN912
C	ASN915
C	ARG919
C	HOH1103

---

site_id	AC5
Number of Residues	4
Details	binding site for residue SO4 D 301

Chain	Residue
D	SER238
D	ARG239
D	HOH404
D	HOH420

---

site_id	AC6
Number of Residues	3
Details	binding site for residue SO4 D 302

Chain	Residue
C	PRO938
C	LYS939
D	ARG214

---

site_id	AC7
Number of Residues	3
Details	binding site for residue SO4 E 1001

Chain	Residue
E	PRO938
E	LYS939
F	ARG214

---

site_id	AC8
Number of Residues	6
Details	binding site for residue SO4 F 302

Chain	Residue
E	ARG913
E	HOH1109
F	SER238
F	ARG239
F	HOH402
F	HOH421

---

site_id	AC9
Number of Residues	6
Details	binding site for residue SO4 G 1001

Chain	Residue
F	ARG254
F	HIS258
G	ASN915
G	ARG919
G	HOH1105
G	HOH1112

---

site_id	AD1
Number of Residues	4
Details	binding site for residue SO4 G 1002

Chain	Residue
A	LYS936
G	PRO938
G	LYS939
G	HOH1110

---

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 H 301

Chain	Residue
G	ARG913
H	SER238
H	ARG239

---

site_id	AD3
Number of Residues	5
Details	binding site for residue SO4 H 302

Chain	Residue
E	ASN915
E	ARG919
H	ARG254
H	HIS258
H	HOH401

---

site_id	AD4
Number of Residues	19
Details	binding site for Di-peptide SO4 B 302 and ARG C 919

Chain	Residue
A	ASP926
A	GLU932
B	GLN251
B	ARG254
B	ARG254
B	ARG255
B	HOH401
B	HOH429
C	ASN915
C	GLU916
C	GLU916
C	LEU917
C	LYS918
C	SER920
C	PHE921
C	PHE922
C	ALA923
C	SO41001
C	HOH1103

---

site_id	AD5
Number of Residues	15
Details	binding site for Di-peptide SO4 F 301 and ARG G 919

Chain	Residue
E	ASP926
E	GLU932
F	ARG254
F	ARG254
G	ASN915
G	GLU916
G	GLU916
G	LEU917
G	LYS918
G	SER920
G	PHE921
G	PHE922
G	ALA923
G	SO41001
G	HOH1112

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000305|PubMed:17217336

Chain	Residue	Details
B	LYS245
D	LYS245
F	LYS245
H	LYS245

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