6G4Q

Structure of human ADP-forming succinyl-CoA ligase complex SUCLG1-SUCLA2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial	polymer	307	32459.1	1	UniProt (P53597) Pfam (PF02629) Pfam (PF00549) In PDB	Homo sapiens (Human)	Succinyl-CoA synthetase subunit alpha,SCS-alpha
2	B	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	polymer	415	45198.3	1	UniProt (Q9P2R7) Pfam (PF08442) Pfam (PF00549) In PDB	Homo sapiens (Human)	ATP-specific succinyl-CoA synthetase subunit beta,A-SCS,Succinyl-CoA synthetase beta-A chain,SCS-betaA
3	A, B	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
4		water	water		18.0	82	Chemie (HOH)

Sequence modifications

A: 42 - 346 (UniProt: P53597)

PDB	External Database	Details
Ser 40	-	expression tag
Met 41	-	expression tag

B: 52 - 463 (UniProt: Q9P2R7)

PDB	External Database	Details
Met 51	-	initiating methionine
Trp 464	-	expression tag
Gln 465	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77657.4
Non-Polymers*	Number of molecules	8
	Total formula weight	496.5
All*	Total formula weight	78153.9

*Water molecules are not included.