6G32
Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Geranylgeranyl pyrophosphate synthase | polymer | 307 | 35484.4 | 6 | UniProt (O95749) Pfam (PF00348) | Homo sapiens (Human) | GGPPSase,(2E,6E)-farnesyl diphosphate synthase,Dimethylallyltranstransferase,Farnesyl diphosphate synthase,Farnesyltranstransferase,Geranylgeranyl diphosphate synthase,Geranyltranstransferase |
| 2 | G, H, I, J, K... (A, B, C, D, E...) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 3 | M (B) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 300 (UniProt: O95749)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gln 109 | Pro 109 | conflict |
| Tyr 188 | Asp 188 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 212906.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 552.6 | |
| All* | Total formula weight | 213458.8 |
