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6G27

X-ray structure of NSD3-PWWP1 in complex with compound 5

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHistone-lysine N-methyltransferase NSD3polymer13616271.41UniProt (Q9BZ95)
Pfam (PF00855)
In PDB
Homo sapiens (Human)Nuclear SET domain-containing protein 3,Protein whistle,WHSC1-like 1 isoform 9 with methyltransferase activity to lysine,Wolf-Hirschhorn syndrome candidate 1-like protein 1,WHSC1-like protein 1
2A5-methyl-6-phenyl-2-piperidin-4-yl-pyridazin-3-onenon-polymer269.31Chemie (EHE)
3waterwater18.0101Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight16271.4
Non-Polymers*Number of molecules1
Total formula weight269.3
All*Total formula weight16540.7
*Water molecules are not included.

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PDB entries from 2024-06-12

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