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6G0W

Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor MCD72

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Poly [ADP-ribose] polymerase 14polymer19322118.62UniProt (Q460N5)
Pfam (PF00644)
Homo sapiens (Human)PARP-14,ADP-ribosyltransferase diphtheria toxin-like 8,ARTD8,B aggressive lymphoma protein 2
2C, D
(A, B)
4-[3-[4-(4-fluorophenyl)piperidin-1-yl]carbonylphenoxy]benzamidenon-polymer418.52Chemie (EGW)
3E, F
(A, B)
waterwater18.021Chemie (HOH)
Sequence modifications
A, B: 1611 - 1801 (UniProt: Q460N5)
PDBExternal DatabaseDetails
Ser 1609-expression tag
Met 1610-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight44237.2
Non-Polymers*Number of molecules2
Total formula weight836.9
All*Total formula weight45074.1
*Water molecules are not included.

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PDB entries from 2025-07-16

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