6G07
RORGT (264-518;C455S) IN COMPLEX WITH INVERSE AGONIST "CPD-9" AND RIP140 PEPTIDE AT 1.66A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Nuclear receptor ROR-gamma | polymer | 257 | 29739.3 | 4 | UniProt (P51449) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | P, Q, R, S | Nuclear receptor-interacting protein 1 | polymer | 20 | 2319.6 | 4 | UniProt (P48552) In PDB | Homo sapiens (Human) | Nuclear factor RIP140,Receptor-interacting protein 140 |
| 3 | A, B, C, D | ~{N}-[5-chloranyl-6-[(1~{S})-1-phenylethoxy]pyridin-3-yl]-2-(4-ethylsulfonylphenyl)ethanamide | non-polymer | 459.0 | 4 | Chemie (EEZ) | |||
| 4 | water | water | 18.0 | 800 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 263 - 518 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Gly 262 | - | expression tag |
| Ser 455 | Cys 455 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 128235.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1835.8 | |
| All* | Total formula weight | 130071.6 |
