6G07
RORGT (264-518;C455S) IN COMPLEX WITH INVERSE AGONIST "CPD-9" AND RIP140 PEPTIDE AT 1.66A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004879 | molecular_function | nuclear receptor activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004879 | molecular_function | nuclear receptor activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue EEZ A 601 |
| Chain | Residue |
| A | CYS285 |
| A | PHE377 |
| A | PHE378 |
| A | PHE388 |
| A | ILE397 |
| A | ILE400 |
| A | SER404 |
| A | HOH795 |
| A | GLN286 |
| A | LEU287 |
| A | CYS320 |
| A | HIS323 |
| A | ARG364 |
| A | MET365 |
| A | ARG367 |
| A | ALA368 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue EEZ B 601 |
| Chain | Residue |
| B | CYS285 |
| B | GLN286 |
| B | LEU287 |
| B | LEU292 |
| B | CYS320 |
| B | HIS323 |
| B | LEU324 |
| B | LEU362 |
| B | ARG364 |
| B | MET365 |
| B | ARG367 |
| B | ALA368 |
| B | PHE377 |
| B | PHE378 |
| B | PHE388 |
| B | ILE400 |
| B | SER404 |
| B | HOH763 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue EEZ C 601 |
| Chain | Residue |
| C | CYS285 |
| C | GLN286 |
| C | LEU287 |
| C | HIS323 |
| C | LEU324 |
| C | ARG364 |
| C | MET365 |
| C | ARG367 |
| C | ALA368 |
| C | PHE377 |
| C | PHE378 |
| C | PHE388 |
| C | ILE400 |
| C | SER404 |
| C | HOH720 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue EEZ D 601 |
| Chain | Residue |
| D | CYS285 |
| D | GLN286 |
| D | LEU287 |
| D | HIS323 |
| D | LEU324 |
| D | ARG364 |
| D | MET365 |
| D | ARG367 |
| D | ALA368 |
| D | PHE377 |
| D | PHE378 |
| D | PHE388 |
| D | ILE397 |
| D | ILE400 |
| D | SER404 |
| D | HOH767 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| P | LYS508 | |
| Q | LYS508 | |
| R | LYS508 | |
| S | LYS508 |
