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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6FVU

26S proteasome, s2 state

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1a, AProteasome subunit alpha type-1polymer24227200.92UniProt (P21243)
Pfam (PF00227)
Pfam (PF10584)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein
2b, BProteasome subunit alpha type-2polymer24927060.62UniProt (P23639)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7
3c, CProteasome subunit alpha type-3polymer24427050.42UniProt (P23638)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13
4d, DProteasome subunit alpha type-4polymer25128202.82UniProt (P40303)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6
5e, EProteasome subunit alpha type-5polymer24927442.82UniProt (P32379)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2
6f, FProteasome subunit alpha type-6polymer23125198.42UniProt (P40302)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5
7g, GProbable proteasome subunit alpha type-7polymer24226734.32UniProt (P21242)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1
8h, 1Proteasome subunit beta type-1polymer19621517.22UniProt (P38624)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3
9i, 2Proteasome subunit beta type-2polymer22624486.82UniProt (P25043)
Pfam (PF00227)
Pfam (PF12465)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1
10j, 3Proteasome subunit beta type-3polymer20422496.62UniProt (P25451)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3
11k, 4Proteasome subunit beta type-4polymer19522218.32UniProt (P22141)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11
12l, 5Proteasome subunit beta type-5polymer21223325.22UniProt (P30656)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2
13m, 6Proteasome subunit beta type-6polymer22224883.92UniProt (P23724)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Multicatalytic endopeptidase complex subunit C5,Proteasome component C5
14n, 7Proteasome subunit beta type-7polymer23225832.32UniProt (P30657)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4
15W26S proteasome regulatory subunit RPN10polymer19721818.61UniProt (P38886)
Pfam (PF13519)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
16VUbiquitin carboxyl-terminal hydrolase RPN11polymer28932491.01UniProt (P43588)
Pfam (PF01398)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)26S proteasome regulatory subunit RPN11,Protein MPR1
17T26S proteasome regulatory subunit RPN12polymer26631111.11UniProt (P32496)
Pfam (PF10075)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Nuclear integrity protein 1
18X26S proteasome regulatory subunit RPN13polymer12714654.61UniProt (O13563)
Pfam (PF04683)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Proteasome non-ATPase subunit 13
19Y26S proteasome complex subunit SEM1polymer8910397.11UniProt (O94742)
Pfam (PF05160)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
20Z26S proteasome regulatory subunit RPN1polymer970106895.91UniProt (P38764)
Pfam (PF17781)
Pfam (PF01851)
Pfam (PF18051)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)HMG-CoA reductase degradation protein 2,Proteasome non-ATPase subunit 1
21N26S proteasome regulatory subunit RPN2polymer922101894.11UniProt (P32565)
Pfam (PF21505)
Pfam (PF01851)
Pfam (PF13646)
Pfam (PF18004)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
22S26S proteasome regulatory subunit RPN3polymer47555378.31UniProt (P40016)
Pfam (PF01399)
Pfam (PF08375)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
23P26S proteasome regulatory subunit RPN5polymer44051341.81UniProt (Q12250)
Pfam (PF01399)
Pfam (PF18098)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Proteasome non-ATPase subunit 5
24Q26S proteasome regulatory subunit RPN6polymer43449839.81UniProt (Q12377)
Pfam (PF18055)
Pfam (PF01399)
Pfam (PF18503)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Proteasome non-ATPase subunit 4
25R26S proteasome regulatory subunit RPN7polymer40546307.51UniProt (Q06103)
Pfam (PF10602)
Pfam (PF01399)
Pfam (PF21154)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
26U26S proteasome regulatory subunit RPN8polymer30434557.31UniProt (Q08723)
Pfam (PF01398)
Pfam (PF13012)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
27O26S proteasome regulatory subunit RPN9polymer38845194.61UniProt (Q04062)
Pfam (PF01399)
Pfam (PF18261)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Proteasome non-ATPase subunit 7
28H26S proteasome regulatory subunit 7 homologpolymer42647318.61UniProt (P33299)
Pfam (PF21236)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein CIM5,Tat-binding homolog 3
29I26S proteasome regulatory subunit 4 homologpolymer38443128.51UniProt (P40327)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Tat-binding homolog 5
30K26S proteasome regulatory subunit 6B homologpolymer39444353.51UniProt (P33298)
Pfam (PF16450)
Pfam (PF00004)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein YNT1,Tat-binding homolog 2
31L26S proteasome subunit RPT4polymer38843931.51UniProt (P53549)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)26S protease subunit SUG2,Proteasomal cap subunit
32M26S proteasome regulatory subunit 6Apolymer42146902.11UniProt (P33297)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Tat-binding protein homolog 1,TBP-1
33J26S proteasome regulatory subunit 8 homologpolymer40545342.71UniProt (Q01939)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein CIM3,Protein SUG1,Tat-binding protein TBY1
34L, M, H, I, KADENOSINE-5'-TRIPHOSPHATEnon-polymer507.25Chemie (ATP)
35K, L, M, J, H...MAGNESIUM IONnon-polymer24.36Chemie (MG)
36JADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains47
Total formula weight1580160.3
Non-Polymers*Number of molecules12
Total formula weight3108.9
All*Total formula weight1583269.2
*Water molecules are not included.

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PDB entries from 2024-04-24

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