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6FVT

26S proteasome, s1 state

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, O
(a, A)
Proteasome subunit alpha type-1polymer24127129.92UniProt (P21243)
Pfam (PF00227)
Pfam (PF10584)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein
2B, P
(b, B)
Proteasome subunit alpha type-2polymer24927060.62UniProt (P23639)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7
3C, Q
(c, C)
Proteasome subunit alpha type-3polymer24427050.42UniProt (P23638)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13
4D, R
(d, D)
Proteasome subunit alpha type-4polymer25128202.82UniProt (P40303)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6
5E, S
(e, E)
Proteasome subunit alpha type-5polymer24426837.12UniProt (P32379)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2
6F, T
(f, F)
Proteasome subunit alpha type-6polymer23125198.42UniProt (P40302)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5
7G, U
(g, G)
Probable proteasome subunit alpha type-7polymer24527005.62UniProt (P21242)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1
8H, V
(h, 1)
Proteasome subunit beta type-1polymer19621517.22UniProt (P38624)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3
9I, W
(i, 2)
Proteasome subunit beta type-2polymer22624486.82UniProt (P25043)
Pfam (PF00227)
Pfam (PF12465)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1
10J, X
(j, 3)
Proteasome subunit beta type-3polymer20422496.62UniProt (P25451)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3
11K, Y
(k, 4)
Proteasome subunit beta type-4polymer19522218.32UniProt (P22141)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11
12L, Z
(l, 5)
Proteasome subunit beta type-5polymer21223325.22UniProt (P30656)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2
13AA, M
(m, 6)
Proteasome subunit beta type-6polymer22224883.92UniProt (P23724)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Multicatalytic endopeptidase complex subunit C5,Proteasome component C5
14BA, N
(n, 7)
Proteasome subunit beta type-7polymer23225832.32UniProt (P30657)
Pfam (PF00227)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4
15CA
(W)
26S proteasome regulatory subunit RPN10polymer19721818.61UniProt (P38886)
Pfam (PF13519)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
16DA
(V)
Ubiquitin carboxyl-terminal hydrolase RPN11polymer28932491.01UniProt (P43588)
Pfam (PF01398)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)26S proteasome regulatory subunit RPN11,Protein MPR1
17EA
(T)
26S proteasome regulatory subunit RPN12polymer26631111.11UniProt (P32496)
Pfam (PF10075)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Nuclear integrity protein 1
18FA
(X)
26S proteasome regulatory subunit RPN13polymer12714654.61UniProt (O13563)
Pfam (PF04683)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Proteasome non-ATPase subunit 13
19GA
(Y)
26S proteasome complex subunit SEM1polymer8910397.11UniProt (O94742)
Pfam (PF05160)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
20HA
(Z)
26S proteasome regulatory subunit RPN1polymer970106895.91UniProt (P38764)
Pfam (PF17781)
Pfam (PF01851)
Pfam (PF18051)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)HMG-CoA reductase degradation protein 2,Proteasome non-ATPase subunit 1
21IA
(N)
26S proteasome regulatory subunit RPN2polymer922101894.11UniProt (P32565)
Pfam (PF21505)
Pfam (PF01851)
Pfam (PF13646)
Pfam (PF18004)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
22JA
(S)
26S proteasome regulatory subunit RPN3polymer47555378.31UniProt (P40016)
Pfam (PF01399)
Pfam (PF08375)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
23KA
(P)
26S proteasome regulatory subunit RPN5polymer44051341.81UniProt (Q12250)
Pfam (PF22241)
Pfam (PF01399)
Pfam (PF18098)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Proteasome non-ATPase subunit 5
24LA
(Q)
26S proteasome regulatory subunit RPN6polymer43449839.81UniProt (Q12377)
Pfam (PF18055)
Pfam (PF01399)
Pfam (PF18503)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Proteasome non-ATPase subunit 4
25MA
(R)
26S proteasome regulatory subunit RPN7polymer40546307.51UniProt (Q06103)
Pfam (PF10602)
Pfam (PF01399)
Pfam (PF21154)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
26NA
(U)
26S proteasome regulatory subunit RPN8polymer30434557.31UniProt (Q08723)
Pfam (PF01398)
Pfam (PF13012)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
27OA
(O)
26S proteasome regulatory subunit RPN9polymer38845194.61UniProt (Q04062)
Pfam (PF22037)
Pfam (PF01399)
Pfam (PF18261)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Proteasome non-ATPase subunit 7
28PA
(H)
26S proteasome regulatory subunit 7 homologpolymer42647318.61UniProt (P33299)
Pfam (PF21236)
Pfam (PF00004)
Pfam (PF17862)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein CIM5,Tat-binding homolog 3
29QA
(I)
26S proteasome regulatory subunit 4 homologpolymer38543229.61UniProt (P40327)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Tat-binding homolog 5
30RA
(K)
26S proteasome regulatory subunit 6B homologpolymer39444353.51UniProt (P33298)
Pfam (PF16450)
Pfam (PF00004)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein YNT1,Tat-binding homolog 2
31SA
(L)
26S proteasome subunit RPT4polymer38843931.51UniProt (P53549)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)26S protease subunit SUG2,Proteasomal cap subunit
32TA
(M)
26S proteasome regulatory subunit 6Apolymer42146902.11UniProt (P33297)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Tat-binding protein homolog 1,TBP-1
33UA
(J)
26S proteasome regulatory subunit 8 homologpolymer40545342.71UniProt (Q01939)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein CIM3,Protein SUG1,Tat-binding protein TBY1
34AB, CB, EB, VA, YA
(K, L, M, H, I)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.25Chemie (ATP)
35BB, DB, GB, WA, XA...
(K, L, J, H, I)
MAGNESIUM IONnon-polymer24.36Chemie (MG)
36FB
(J)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains47
Total formula weight1579450.4
Non-Polymers*Number of molecules12
Total formula weight3108.9
All*Total formula weight1582559.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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