6FUK
Crystal structure of UTX complexed with 5-carboxy-8-hydroxyquinoline
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Lysine-specific demethylase 6A | polymer | 531 | 60264.4 | 1 | UniProt (O15550) Pfam (PF02373) Pfam (PF21322) Pfam (PF21326) In PDB | Homo sapiens (Human) | Histone demethylase UTX,Ubiquitously-transcribed TPR protein on the X chromosome,Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein |
| 2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | A | 8-hydroxyquinoline-5-carboxylic acid | non-polymer | 189.2 | 1 | Chemie (8XQ) | |||
| 4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 7 | A | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 1 | Chemie (PG0) | |||
| 8 | water | water | 18.0 | 269 | Chemie (HOH) |
Sequence modifications
A: 877 - 1401 (UniProt: O15550)
| PDB | External Database | Details |
|---|---|---|
| Gly 871 | - | expression tag |
| Pro 872 | - | expression tag |
| Gly 873 | - | expression tag |
| Tyr 874 | - | expression tag |
| Gln 875 | - | expression tag |
| Asp 876 | - | expression tag |
| Asn 878 | Ser 878 | conflict |
| Ser 879 | Pro 879 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60264.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 834.0 | |
| All* | Total formula weight | 61098.4 |
