6FUJ
Complement factor D in complex with the inhibitor N-(3'-(aminomethyl)-[1,1'-biphenyl]-3-yl)-3-methylbutanamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Complement factor D | polymer | 232 | 24739.1 | 6 | UniProt (P00746) Pfam (PF00089) | Homo sapiens (Human) | Adipsin,C3 convertase activator,Properdin factor D |
| 2 | G, H, I (A, B, C) | ~{N}-[3-[3-(aminomethyl)phenyl]phenyl]-3-methyl-butanamide | non-polymer | 282.4 | 3 | Chemie (E8B) | |||
| 3 | J, K, L, M, N... (A, B, C, D, E...) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 16 - 243 (UniProt: P00746)
| PDB | External Database | Details |
|---|---|---|
| Ser 244 | - | expression tag |
| Ala 245 | - | expression tag |
| Ala 246 | - | expression tag |
| Ala 247 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 148434.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 847.1 | |
| All* | Total formula weight | 149281.9 |
