6FR0
Crystal structure of CREBBP bromodomain complexd with PB08
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CREB-binding protein | polymer | 119 | 14223.3 | 2 | UniProt (Q92793) Pfam (PF00439) | Homo sapiens (Human) | |
| 2 | C, D (A, B) | ~{N}-[3-(5-ethanoyl-2-ethoxy-phenyl)-5-(2-ethyl-5-methyl-3-oxidanylidene-1,2-oxazol-4-yl)phenyl]furan-2-carboxamide | non-polymer | 474.5 | 2 | Chemie (E3H) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A, B: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28446.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 949.0 | |
| All* | Total formula weight | 29395.7 |
