6FQS

3.11A complex of S.Aureus gyrase with imidazopyrazinone T3 and DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, D	DNA gyrase subunit B,DNA gyrase subunit B	polymer	202	22605.7	2	UniProt (P66937) Pfam (PF01751) Pfam (PF00986) In PDB	Staphylococcus aureus (strain N315)
2	A	DNA gyrase subunit A	polymer	490	55537.3	1	UniProt (Q99XG5) Pfam (PF00521) In PDB	Staphylococcus aureus
3	C	DNA gyrase subunit A	polymer	490	55617.3	1	UniProt (Q99XG5) Pfam (PF00521) In PDB	Staphylococcus aureus
4	E, F	DNA (5'-D(*GP*AP*GP*AP*GP*TP*AP*T*GP*GP*CP*CP*AP*TP*AP*CP*TP*CP*TP*T)-3')	polymer	20	6149.0	2		synthetic construct
5	B, D	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
6	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
7	A, C, E	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
8	C	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
9	E	5-cyclopropyl-8-fluoranyl-7-pyridin-4-yl-imidazo[1,2-a]quinoxalin-4-one	non-polymer		320.3	2	Chemie (E3E)
10		water	water		18.0	112	Chemie (HOH)

Sequence modifications

B, D: 409 - 543 (UniProt: P66937)

PDB	External Database	Details
Met 409	Leu 409	conflict

B, D: 580 - 644 (UniProt: P66937)

PDB	External Database	Details
Thr 544	-	linker
Gly 579	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	168664.0
Non-Polymers*	Number of molecules	14
	Total formula weight	1606.3
All*	Total formula weight	170270.3

*Water molecules are not included.