6FQM
3.06A COMPLEX OF S.AUREUS GYRASE with imidazopyrazinone T1 AND DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, b, d | DNA gyrase subunit B | polymer | 201 | 22474.5 | 3 | UniProt (P66937) Pfam (PF01751) Pfam (PF00986) In PDB | Staphylococcus aureus subsp. aureus N315 | |
| 2 | A, C, a, c | DNA gyrase subunit A | polymer | 490 | 55617.3 | 4 | UniProt (Q99XG5) Pfam (PF00521) In PDB | Staphylococcus aureus subsp. aureus N315 | |
| 3 | D | DNA gyrase subunit B | polymer | 202 | 22605.7 | 1 | UniProt (P66937) Pfam (PF01751) Pfam (PF00986) In PDB | Staphylococcus aureus subsp. aureus N315 | |
| 4 | E, F, e, f | DNA (5'-D(*GP*AP*GP*AP*GP*TP*AP*T*GP*GP*CP*CP*AP*TP*AP*CP*TP*CP*T)-3') | polymer | 20 | 6149.0 | 4 | synthetic construct | ||
| 5 | B, D, b, d | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 6 | C, c | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | E, F, e, f | 7-[(3~{S})-3-azanylpyrrolidin-1-yl]-5-cyclopropyl-8-fluoranyl-imidazo[1,2-a]quinoxalin-4-one | non-polymer | 327.4 | 6 | Chemie (E32) | |||
| 8 | E | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 9 | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
B, b, d: 410 - 644 (UniProt: P66937)
D: 410 - 644 (UniProt: P66937)
| PDB | External Database | Details |
|---|---|---|
| - | Leu 544 | deletion |
| - | Tyr 545 | deletion |
| - | Lys 546 | deletion |
| - | Leu 547 | deletion |
| - | Thr 548 | deletion |
| - | Gln 549 | deletion |
| - | Gly 550 | deletion |
| - | Lys 551 | deletion |
| - | Gln 552 | deletion |
| - | Lys 553 | deletion |
| - | Tyr 554 | deletion |
| - | Tyr 555 | deletion |
| - | Val 556 | deletion |
| - | Tyr 557 | deletion |
| - | Asn 558 | deletion |
| - | Asp 559 | deletion |
| - | Arg 560 | deletion |
| - | Glu 561 | deletion |
| - | Leu 562 | deletion |
| - | Asp 563 | deletion |
| - | Lys 564 | deletion |
| - | Leu 565 | deletion |
| - | Lys 566 | deletion |
| - | Ser 567 | deletion |
| - | Glu 568 | deletion |
| - | Leu 569 | deletion |
| - | Asn 570 | deletion |
| - | Pro 571 | deletion |
| - | Thr 572 | deletion |
| - | Pro 573 | deletion |
| - | Lys 574 | deletion |
| - | Trp 575 | deletion |
| - | Ser 576 | deletion |
| - | Ile 577 | deletion |
| Thr 578 | Ala 578 | conflict |
| Gly 579 | Arg 579 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 409 | - | initiating methionine |
| Thr 578 | Ala 578 | conflict |
| Gly 579 | Arg 579 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 337094.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2468.1 | |
| All* | Total formula weight | 339562.4 |
