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6FQH

GluA2(flop) S729C ligand binding core dimer bound to NBQX at 1.76 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Glutamate receptor 2,Glutamate receptor 2polymer27630417.02UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (Norway Rat)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2C, D
(A, B)
6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamidenon-polymer336.32Chemie (E2Q)
3E, F
(A, B)
waterwater18.0458Chemie (HOH)
Sequence modifications
A, B: -10 - 117 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly -11-expression tag
Ser -10Thr 400conflict
Ala -9Glu 401conflict
Met -8Leu 402conflict
Gly -7Pro 403conflict
Arg 0Gly 410conflict
Gly 1Leu 411conflict
Ala 2Glu 412conflict
A, B: 120 - 264 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 118-linker
Thr 119-linker
Cys 217Ser 750conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight60833.9
Non-Polymers*Number of molecules2
Total formula weight672.6
All*Total formula weight61506.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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