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6FQH

GluA2(flop) S729C ligand binding core dimer bound to NBQX at 1.76 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BGlutamate receptor 2,Glutamate receptor 2polymer27630417.02UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
Pfam (PF00497)
In PDB
Rattus norvegicus (Norway Rat)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2A, B6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamidenon-polymer336.32Chemie (E2Q)
3waterwater18.0458Chemie (HOH)
Sequence modifications
A, B: -10 - 117 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly -11-expression tag
Ser -10Thr 400conflict
Ala -9Glu 401conflict
Met -8Leu 402conflict
Gly -7Pro 403conflict
Arg 0Gly 410conflict
Gly 1Leu 411conflict
Ala 2Glu 412conflict
A, B: 120 - 264 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 118-linker
Thr 119-linker
Cys 217Ser 750conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight60833.9
Non-Polymers*Number of molecules2
Total formula weight672.6
All*Total formula weight61506.5
*Water molecules are not included.

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PDB entries from 2024-05-01

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