6FOL
Domain II of the human copper chaperone in complex with human Cu,Zn superoxide dismutase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, E, H (A, D, E, H) | Copper chaperone for superoxide dismutase | polymer | 150 | 15816.5 | 4 | UniProt (O14618) Pfam (PF00080) | Homo sapiens (Human) | Superoxide dismutase copper chaperone |
| 2 | B, C, F, G (B, C, F, G) | Superoxide dismutase [Cu-Zn] | polymer | 153 | 15763.4 | 4 | UniProt (P00441) Pfam (PF00080) | Homo sapiens (Human) | Superoxide dismutase 1,hSod1 |
| 3 | I, J, K, L, O... (A, B, C, D, E...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | M, N (D) | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL | non-polymer | 370.4 | 2 | Chemie (PE8) | |||
| 5 | Q (F) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | AA, T, U, V, W... (H, A, B, C, D...) | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A, D, E, H: 85 - 232 (UniProt: O14618)
B, C, F, G: 1 - 153 (UniProt: P00441)
| PDB | External Database | Details |
|---|---|---|
| Gly 83 | - | expression tag |
| Ala 84 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 57 | Cys 58 | engineered mutation |
| Ala 146 | Cys 147 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 126319.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1356.2 | |
| All* | Total formula weight | 127676.0 |
