6FO6
CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial inhibitor SCR0911
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, J (E, R) | Cytochrome b-c1 complex subunit Rieske, mitochondrial | polymer | 274 | 29586.8 | 2 | UniProt (P13272) Pfam (PF00355) Pfam (PF09165) Pfam (PF02921) | Bos taurus (Bovine) | Complex III subunit 5,Cytochrome b-c1 complex subunit 5,Rieske iron-sulfur protein,RISP,Rieske protein UQCRFS1,Ubiquinol-cytochrome c reductase iron-sulfur subunit |
| 2 | B, K (A, N) | Cytochrome b-c1 complex subunit 1, mitochondrial | polymer | 480 | 52796.4 | 2 | UniProt (P31800) Pfam (PF00675) Pfam (PF05193) | Bos taurus (Bovine) | Complex III subunit 1,Core protein I,Ubiquinol-cytochrome-c reductase complex core protein 1 |
| 3 | C, L (B, O) | Cytochrome b-c1 complex subunit 2, mitochondrial | polymer | 453 | 48203.4 | 2 | UniProt (P23004) Pfam (PF00675) Pfam (PF05193) | Bos taurus (Bovine) | Complex III subunit 2,Core protein II,Ubiquinol-cytochrome-c reductase complex core protein 2 |
| 4 | D, M (C, P) | Cytochrome b | polymer | 379 | 42620.3 | 2 | UniProt (P00157) Pfam (PF00033) Pfam (PF00032) | Bos taurus (Bovine) | Complex III subunit 3,Complex III subunit III,Cytochrome b-c1 complex subunit 3,Ubiquinol-cytochrome-c reductase complex cytochrome b subunit |
| 5 | E, N (D, Q) | Cytochrome c1, heme protein, mitochondrial | polymer | 325 | 35343.8 | 2 | UniProt (P00125) Pfam (PF02167) | Bos taurus (Bovine) | Complex III subunit 4,Complex III subunit IV,Cytochrome b-c1 complex subunit 4,Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit,Cytochrome c-1 |
| 6 | F, O (F, S) | Cytochrome b-c1 complex subunit 7 | polymer | 111 | 13502.4 | 2 | UniProt (P00129) Pfam (PF02271) | Bos taurus (Bovine) | Complex III subunit 7,Complex III subunit VII,QP-C,Ubiquinol-cytochrome c reductase complex 14 kDa protein |
| 7 | G, P (G, T) | Cytochrome b-c1 complex subunit 8 | polymer | 82 | 9737.2 | 2 | UniProt (P13271) Pfam (PF02939) | Bos taurus (Bovine) | Complex III subunit 8,Complex III subunit VIII,Ubiquinol-cytochrome c reductase complex 9.5 kDa protein,Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C |
| 8 | H, Q (H, U) | Cytochrome b-c1 complex subunit 6, mitochondrial | polymer | 91 | 10638.7 | 2 | UniProt (P00126) Pfam (PF02320) | Bos taurus (Bovine) | Complex III subunit 6,Complex III subunit VIII,Cytochrome c1 non-heme 11 kDa protein,Mitochondrial hinge protein,Ubiquinol-cytochrome c reductase complex 11 kDa protein |
| 9 | I, R (J, W) | Cytochrome b-c1 complex subunit 9 | polymer | 64 | 7469.6 | 2 | UniProt (P00130) Pfam (PF05365) | Bos taurus (Bovine) | Complex III subunit 9,Complex III subunit X,Cytochrome c1 non-heme 7 kDa protein,Ubiquinol-cytochrome c reductase complex 7.2 kDa protein |
| 10 | S, T, W, X (C, P) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 11 | U, Y (C, P) | 7-methoxy-3-methyl-2-[5-[4-(trifluoromethyloxy)phenyl]pyridin-3-yl]quinolin-4-ol | non-polymer | 426.4 | 2 | Chemie (DY2) | |||
| 12 | V, Z (D, Q) | HEME C | non-polymer | 618.5 | 2 | Chemie (HEC) |
Sequence modifications
F, S: 0 - 110 (UniProt: P00129)
| PDB | External Database | Details |
|---|---|---|
| Asp 56 | Asn 57 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 499797.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4555.7 | |
| All* | Total formula weight | 504353.3 |
