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6FNW

Structure of a volume-regulated anion channel of the LRRC8 family

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Volume-regulated anion channel subunit LRRC8Apolymer41748155.11UniProt (Q80WG5)
Pfam (PF13855)
Mus musculus (Mouse)Leucine-rich repeat-containing protein 8A
2B, C, D, E
(A)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
3F
(A)
waterwater18.0337Chemie (HOH)
Sequence modifications
A: 398 - 810 (UniProt: Q80WG5)
PDBExternal DatabaseDetails
Gly 395-expression tag
Pro 396-expression tag
Ser 397-expression tag
Ala 811-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight48155.1
Non-Polymers*Number of molecules4
Total formula weight248.3
All*Total formula weight48403.4
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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