6FNF
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with NVP-BHG712
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Ephrin type-A receptor 2 | polymer | 306 | 34462.8 | 1 | UniProt (P29317) Pfam (PF07714) In PDB | Homo sapiens (Human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
| 2 | A | 4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{N}-[3-(trifluoromethyl)phenyl]benzamide | non-polymer | 503.5 | 1 | Chemie (DXH) | |||
| 3 | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A: 596 - 900 (UniProt: P29317)
| PDB | External Database | Details |
|---|---|---|
| Gly 595 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34462.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 503.5 | |
| All* | Total formula weight | 34966.3 |
