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6FL1

Crystal structure of the complex between the Lactococcus lactis FPG mutant T221P and a Fapy-dG containing DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
DNA (5'-D(*CP*TP*CP*TP*TP*TP(FOX)P*TP*TP*TP*CP*TP*CP*G)-3')polymer144219.81synthetic construct
2B
(C)
DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3')polymer144355.91synthetic construct
3C
(A)
Formamidopyrimidine-DNA glycosylasepolymer27131112.21UniProt (A0A165FVI1)Lactococcus lactis subsp. cremoris (Streptococcus cremoris)Fapy-DNA glycosylase,DNA-(apurinic or apyrimidinic site) lyase MutM,AP lyase MutM
4D
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5E, F, G
(B, C, A)
waterwater18.0459Chemie (HOH)
Sequence modifications
A: 1 - 271 (UniProt: A0A165FVI1)
PDBExternal DatabaseDetails
Pro 221Thr 222engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight39687.9
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight39753.3
*Water molecules are not included.

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PDB entries from 2025-12-03

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