6FKO

Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP, dGMP, hadacidin at 2.1 Angstrom resolution

Replaces:  6FJR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Adenylosuccinate synthetase	polymer	363	40393.0	2	UniProt (G3FFN6) Pfam (PF00709)	Vibrio phage phiVC8
2	C (A)	HADACIDIN	non-polymer		119.1	1	Chemie (HDA) PubChem (12717)
3	D, G (A, B)	2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE	non-polymer		347.2	2	Chemie (DGP) PubChem (135398597) PubChem (135402021) PubChem (135596592) PubChem (135699677) PubChem (135794130) PubChem (135873587) PubChem (135873588) PubChem (135925427) PubChem (135933899) PubChem (136093899) PubChem (136269908) PubChem (136847913) PubChem (137226753) PubChem (137257916)
4	E (A)	CITRATE ANION	non-polymer		189.1	1	Chemie (FLC) PubChem (31348)
5	F, H (A, B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
6	I, J (A, B)	water	water		18.0	532	Chemie (HOH)

Sequence modifications

A, B: 3 - 343 (UniProt: G3FFN6)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Met 1	-	expression tag
Glu 2	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80786.0
Non-Polymers*	Number of molecules	6
	Total formula weight	2017.0
All*	Total formula weight	82803.0

*Water molecules are not included.