6FJD

Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 4,5-bisphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein KIBRA	polymer	140	15866.0	2	UniProt (Q8IX03) Pfam (PF00168) In PDB	Homo sapiens (Human)	HBeAg-binding protein 3,Kidney and brain protein,KIBRA,WW domain-containing protein 1
2	A, B	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
3	A, B	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
4	A	(2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE	non-polymer		634.4	1	Chemie (PBU)
5		water	water		18.0	53	Chemie (HOH)

Sequence modifications

A, B: 658 - 785 (UniProt: Q8IX03)

PDB	External Database	Details
Met 646	-	initiating methionine
Arg 647	-	expression tag
Gly 648	-	expression tag
Ser 649	-	expression tag
His 650	-	expression tag
His 651	-	expression tag
His 652	-	expression tag
His 653	-	expression tag
His 654	-	expression tag
His 655	-	expression tag
Gly 656	-	expression tag
Ser 657	-	expression tag
Ala 771	Cys 771	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31732.1
Non-Polymers*	Number of molecules	13
	Total formula weight	1755.4
All*	Total formula weight	33487.4

*Water molecules are not included.