6FIJ

Structure of the loading/condensing region (SAT-KS-MAT) of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Polyketide synthase	polymer	1304	140303.1	2	UniProt (Q6DQW3) Pfam (PF16073) Pfam (PF00109) Pfam (PF02801) Pfam (PF22621) Pfam (PF00698)	Cercospora nicotianae (Barn spot disease fungus)
2	C, D, E, F, G... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
3	I, J (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	Q (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	R (B)	2,3-DIHYDROXY-1,4-DITHIOBUTANE	non-polymer		154.3	1	Chemie (DTT)
6	S, T (A, B)	water	water		18.0	352	Chemie (HOH)

Sequence modifications

A, B: 1 - 1293 (UniProt: Q6DQW3)

PDB	External Database	Details
Ala 321	Thr 321	engineered mutation
Ala 1294	-	expression tag
Ala 1295	-	expression tag
Ala 1296	-	expression tag
Leu 1297	-	expression tag
Glu 1298	-	expression tag
His 1299	-	expression tag
His 1300	-	expression tag
His 1301	-	expression tag
His 1302	-	expression tag
His 1303	-	expression tag
His 1304	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	280606.1
Non-Polymers*	Number of molecules	16
	Total formula weight	1107.6
All*	Total formula weight	281713.7

*Water molecules are not included.