6FIB

Structure of human 4-1BB ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tumor necrosis factor ligand superfamily member 9	polymer	188	19439.9	1	UniProt (P41273) Pfam (PF00229) In PDB	Homo sapiens (Human)	4-1BB ligand,4-1BBL
2	B	Tumor necrosis factor ligand superfamily member 9,4-1BBL -CH/CL fusion	polymer	311	32892.0	1	UniProt (P41273) Pfam (PF00229) In PDB	Homo sapiens (Human)	4-1BB ligand,4-1BBL
3	C	Tumor necrosis factor ligand superfamily member 9,Uncharacterized protein	polymer	292	30164.9	1	UniProt (P41273) UniProt (A8K008) Pfam (PF00229) In PDB	Homo sapiens (Human)	4-1BB ligand,4-1BBL
4		water	water		18.0	82	Chemie (HOH)

Sequence modifications

A: 71 - 248 (UniProt: P41273)

PDB	External Database	Details
Gly 249	-	expression tag
Gly 250	-	expression tag
Gly 251	-	expression tag
Gly 252	-	expression tag
Ser 253	-	expression tag
Gly 254	-	expression tag
Gly 255	-	expression tag
Gly 256	-	expression tag
Gly 257	-	expression tag
Ser 258	-	expression tag

B: 71 - 248 (UniProt: P41273)
B: 249 - 381 (PDB: 6FIB)
C: 71 - 248 (UniProt: P41273)

PDB	External Database	Details
Arg 70	-	expression tag
Gly 249	-	linker
Gly 250	-	linker
Gly 251	-	linker
Gly 252	-	linker
Ser 253	-	linker
Gly 254	-	linker
Gly 255	-	linker
Gly 256	-	linker
Gly 257	-	linker

C: 258 - 361 (UniProt: A8K008)

PDB	External Database	Details
Glu 288	Lys 172	conflict
Glu 354	Lys 238	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	82496.9
All*	Total formula weight	82496.9

*Water molecules are not included.