6FGO
Fc in complex with engineered calcium binding domain Z
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, B, C, D) | Immunoglobulin gamma-1 heavy chain | polymer | 210 | 23820.9 | 4 | UniProt (P0DOX5) Pfam (PF07654) | Homo sapiens (Human) | Immunoglobulin gamma-1 heavy chain NIE |
| 2 | B, D, F, H (E, F, G, H) | Z-Ca | polymer | 69 | 7665.4 | 4 | Pfam (PF02216) UniProt (by SIFTS) (A0A0U3TLJ6) | Staphylococcus aureus | |
| 3 | I, K (I, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1463.3 | 2 | In PDB GlyTouCan (G80858MF) | |||
| 4 | J (J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1260.2 | 1 | In PDB GlyTouCan (G45889JQ) | |||
| 5 | L (L) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 6 | HA, IA, JA, M, N (C, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 7 | AA, BA, KA, LA, MA... (F, C, A, D, E...) | GLYCEROL | non-polymer | 92.1 | 15 | Chemie (GOL) | |||
| 8 | NA, R, SA, Z (G, E, H, F) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 9 | CA, DA, EA, FA, GA... (C, D, B) | CHLORIDE ION | non-polymer | 35.5 | 9 | Chemie (CL) | |||
| 10 | AB, TA, UA, VA, WA... (H, A, E, B, F...) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 237 - 446 (UniProt: P0DOX5)
| PDB | External Database | Details |
|---|---|---|
| Glu 356 | Asp 358 | conflict |
| Met 358 | Leu 360 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 125945.2 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 5097.7 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 2391.4 | |
| All* | Total formula weight | 133434.3 |
