6FFE
Human BRD2 C-terminal bromodomain with 2-((4-acetyl-3-cyclopropyl-3,4-dihydroquinoxalin-1(2H)-yl)methyl)benzoic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bromodomain-containing protein 2 | polymer | 115 | 13432.5 | 1 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
2 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
4 | A | 2-((4-acetyl-3-cyclopropyl-3,4-dihydroquinoxalin-1(2H)-yl)methyl)benzoic acid | non-polymer | 350.4 | 1 | Chemie (D7Q) | |||
5 | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A: 344 - 455 (UniProt: P25440)
PDB | External Database | Details |
---|---|---|
Gly 341 | - | expression tag |
Ser 342 | - | expression tag |
Met 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13432.5 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 686.8 | |
All* | Total formula weight | 14119.2 |