6FD0

Human KIBRA C2 domain mutant M734I S735A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein KIBRA	polymer	140	15864.1	2	UniProt (Q8IX03) Pfam (PF00168) In PDB	Homo sapiens (Human)	HBeAg-binding protein 3,Kidney and brain protein,KIBRA,WW domain-containing protein 1
2	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
3	A, B	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4		water	water		18.0	2	Chemie (HOH)

Sequence modifications

A, B: 658 - 785 (UniProt: Q8IX03)

PDB	External Database	Details
Met 646	-	initiating methionine
Arg 647	-	expression tag
Gly 648	-	expression tag
Ser 649	-	expression tag
His 650	-	expression tag
His 651	-	expression tag
His 652	-	expression tag
His 653	-	expression tag
His 654	-	expression tag
His 655	-	expression tag
Gly 656	-	expression tag
Ser 657	-	expression tag
Ile 734	Met 734	engineered mutation
Ala 735	Ser 735	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31728.1
Non-Polymers*	Number of molecules	4
	Total formula weight	382.4
All*	Total formula weight	32110.5

*Water molecules are not included.