6FD0
Human KIBRA C2 domain mutant M734I S735A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein KIBRA | polymer | 140 | 15864.1 | 2 | UniProt (Q8IX03) Pfam (PF00168) | Homo sapiens (Human) | HBeAg-binding protein 3,Kidney and brain protein,KIBRA,WW domain-containing protein 1 |
| 2 | C (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 3 | D, E, F (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, B: 658 - 785 (UniProt: Q8IX03)
| PDB | External Database | Details |
|---|---|---|
| Met 646 | - | initiating methionine |
| Arg 647 | - | expression tag |
| Gly 648 | - | expression tag |
| Ser 649 | - | expression tag |
| His 650 | - | expression tag |
| His 651 | - | expression tag |
| His 652 | - | expression tag |
| His 653 | - | expression tag |
| His 654 | - | expression tag |
| His 655 | - | expression tag |
| Gly 656 | - | expression tag |
| Ser 657 | - | expression tag |
| Ile 734 | Met 734 | engineered mutation |
| Ala 735 | Ser 735 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31728.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 382.4 | |
| All* | Total formula weight | 32110.5 |
