6FCV

Structure of the human DDB1-CSA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA damage-binding protein 1	polymer	1158	129253.9	1	UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) In PDB	Homo sapiens (Human)	DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe
2	B	DNA excision repair protein ERCC-8	polymer	416	46441.7	1	UniProt (Q13216) Pfam (PF00400) In PDB	Homo sapiens (Human)	Cockayne syndrome WD repeat protein CSA

Sequence modifications

A: 1 - 1140 (UniProt: Q16531)

PDB	External Database	Details
Met -17	-	initiating methionine
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Arg -10	-	expression tag
Arg -9	-	expression tag
Leu -8	-	expression tag
Val -7	-	expression tag
Pro -6	-	expression tag
Arg -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Arg 0	-	expression tag

B: 1 - 396 (UniProt: Q13216)

PDB	External Database	Details
Leu 397	-	expression tag
Ala 398	-	expression tag
Leu 399	-	expression tag
Val 400	-	expression tag
Pro 401	-	expression tag
Arg 402	-	expression tag
Gly 403	-	expression tag
Ser 404	-	expression tag
Ser 405	-	expression tag
Ala 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag
His 409	-	expression tag
His 410	-	expression tag
His 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	175695.6
All*	Total formula weight	175695.6

*Water molecules are not included.