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6FCP

Crystal structure of 14-3-3 sigma in complex with Shroom3 P1244L

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer23626542.91UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B
(P)
Protein Shroom3polymer151591.71UniProt (Q8TF72)Homo sapiensShroom-related protein,hShrmL
3C, D
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4E, F
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
5G, H
(A, P)
waterwater18.0400Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
P: 1233 - 1247 (UniProt: Q8TF72)
PDBExternal DatabaseDetails
Leu 1244Pro 1244variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28134.6
Non-Polymers*Number of molecules4
Total formula weight119.5
All*Total formula weight28254.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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