6FCP

Crystal structure of 14-3-3 sigma in complex with Shroom3 P1244L

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	14-3-3 protein sigma	polymer	236	26542.9	1	UniProt (P31947) Pfam (PF00244) In PDB	Homo sapiens (Human)	Epithelial cell marker protein 1,Stratifin
2	P	Protein Shroom3	polymer	15	1591.7	1	UniProt (Q8TF72) In PDB	Homo sapiens	Shroom-related protein,hShrmL
3	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5		water	water		18.0	400	Chemie (HOH)

Sequence modifications

A: 1 - 231 (UniProt: P31947)

PDB	External Database	Details
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

P: 1233 - 1247 (UniProt: Q8TF72)

PDB	External Database	Details
Leu 1244	Pro 1244	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28134.6
Non-Polymers*	Number of molecules	4
	Total formula weight	119.5
All*	Total formula weight	28254.1

*Water molecules are not included.