6FC0

Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Eukaryotic translation initiation factor 4E-like protein	polymer	200	23081.3	1	UniProt (G0SCU4) Pfam (PF01652)	Chaetomium thermophilum var. thermophilum DSM 1495
2	B (B)	Eukaryotic translation initiation factor 4G	polymer	81	9048.3	1	UniProt (G0SFP0) Pfam (PF12152)	Chaetomium thermophilum var. thermophilum DSM 1495
3	C, D (A, B)	water	water		18.0	230	Chemie (HOH)

Sequence modifications

A: 35 - 250 (UniProt: G0SCU4)

PDB	External Database	Details
Gly 31	-	expression tag
Pro 32	-	expression tag
His 33	-	expression tag
Met 34	-	expression tag
-	Gly 183	deletion
-	Arg 184	deletion
-	His 185	deletion
-	Ile 186	deletion
-	Ala 187	deletion
-	Ser 188	deletion
-	Arg 189	deletion
-	Gly 190	deletion
-	Asp 191	deletion
-	Gly 192	deletion
-	Asp 193	deletion
-	Val 194	deletion
-	Ala 195	deletion
-	Gly 196	deletion
-	Gly 197	deletion
-	Lys 198	deletion
-	Gly 199	deletion
-	Arg 200	deletion
-	Ser 201	deletion
-	Leu 202	deletion

B: 954 - 1030 (UniProt: G0SFP0)

PDB	External Database	Details
Gly 950	-	expression tag
Pro 951	-	expression tag
His 952	-	expression tag
Met 953	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32129.6
All*	Total formula weight	32129.6

*Water molecules are not included.