6FBZ

Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum in the cap-bound state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Eukaryotic translation initiation factor 4E-like protein,Eukaryotic translation initiation factor 4E-like protein	polymer	200	23081.3	1	UniProt (G0SCU4) Pfam (PF01652) In PDB	Chaetomium thermophilum var. thermophilum DSM 1495
2	B	Eukaryotic translation initiation factor 4G	polymer	81	9048.3	1	UniProt (G0SFP0) Pfam (PF12152) In PDB	Chaetomium thermophilum var. thermophilum DSM 1495
3	A	7-METHYL-GUANOSINE-5'-TRIPHOSPHATE	non-polymer		538.2	1	Chemie (MGP)
4		water	water		18.0	134	Chemie (HOH)

Sequence modifications

A: 35 - 182 (UniProt: G0SCU4)

PDB	External Database	Details
Gly 31	-	expression tag
Pro 32	-	expression tag
His 33	-	expression tag
Met 34	-	expression tag

A: 203 - 250 (UniProt: G0SCU4)
B: 954 - 1030 (UniProt: G0SFP0)

PDB	External Database	Details
Gly 950	-	expression tag
Pro 951	-	expression tag
His 952	-	expression tag
Met 953	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32129.6
Non-Polymers*	Number of molecules	1
	Total formula weight	538.2
All*	Total formula weight	32667.8

*Water molecules are not included.