6FBW

Crystal structure of C-terminal modified Tau peptide-hybrid 4.2f-II with 14-3-3sigma

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	14-3-3 protein sigma	polymer	236	26542.9	2	UniProt (P31947) Pfam (PF00244) In PDB	Homo sapiens (Human)	Epithelial cell marker protein 1,Stratifin
2	B, D	ARG-THR-PRO-SEP-LEU-PRO-GLY	polymer	7	807.8	2	UniProt (by SIFTS) (P10636) In PDB	Homo sapiens
3	A, C	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	A	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
5	B, D	(2~{R})-2-[(~{S})-(3-methoxyphenyl)-phenyl-methyl]pyrrolidine	non-polymer		267.4	2	Chemie (D4K)
6		water	water		18.0	670	Chemie (HOH)

Sequence modifications

A, C: 1 - 231 (UniProt: P31947)

PDB	External Database	Details
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	54701.4
Non-Polymers*	Number of molecules	8
	Total formula weight	697.6
All*	Total formula weight	55399.0

*Water molecules are not included.