6FBR
Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human MEp DR1 Response Element, pH 4.2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Retinoic acid receptor RXR-alpha | polymer | 87 | 10262.9 | 2 | UniProt (P19793) Pfam (PF00105) | Homo sapiens (Human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| 2 | C (C) | DNA (5'-D(*CP*TP*GP*GP*GP*TP*CP*AP*AP*AP*GP*TP*TP*CP*AP*TP*C)-3') | polymer | 17 | 5202.4 | 1 | Homo sapiens | ||
| 3 | D (D) | DNA (5'-D(*GP*AP*TP*GP*AP*AP*CP*TP*TP*TP*GP*AP*CP*CP*CP*AP*G)-3') | polymer | 17 | 5211.4 | 1 | Homo sapiens | ||
| 4 | E, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | G (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | H (B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 7 | I, J (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 8 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A, B: 130 - 212 (UniProt: P19793)
| PDB | External Database | Details |
|---|---|---|
| Gly 126 | - | expression tag |
| Ser 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 30939.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 588.2 | |
| All* | Total formula weight | 31527.8 |
