6FBA
Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor 2,3-naphthalenediol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Aspartate transcarbamoylase | polymer | 349 | 40350.8 | 2 | UniProt (O15804) Pfam (PF02729) Pfam (PF00185) In PDB | Plasmodium falciparum (malaria parasite P. falciparum) | |
2 | C | Aspartate transcarbamoylase | polymer | 349 | 40366.8 | 1 | UniProt (O15804) Pfam (PF02729) Pfam (PF00185) In PDB | Plasmodium falciparum (malaria parasite P. falciparum) | |
3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | A, B, C | naphthalene-2,3-diol | non-polymer | 160.2 | 3 | Chemie (D48) | |||
5 | A, B, C | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
6 | A, C | MALONATE ION | non-polymer | 102.0 | 3 | Chemie (MLI) | |||
7 | A, C | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
8 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
9 | B, C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
10 | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A, B: 37 - 375 (UniProt: O15804)
C: 37 - 375 (UniProt: O15804)
PDB | External Database | Details |
---|---|---|
Ser 376 | - | expression tag |
Ala 377 | - | expression tag |
Trp 378 | - | expression tag |
Ser 379 | - | expression tag |
His 380 | - | expression tag |
Pro 381 | - | expression tag |
Gln 382 | - | expression tag |
Phe 383 | - | expression tag |
Glu 384 | - | expression tag |
Lys 385 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser 376 | - | expression tag |
Ala 377 | - | expression tag |
Trp 378 | - | expression tag |
Ser 379 | - | expression tag |
His 380 | - | expression tag |
Pro 381 | - | expression tag |
Gln 382 | - | expression tag |
Phe 383 | - | expression tag |
Glu 384 | - | expression tag |
Lys 385 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 121068.3 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 1632.6 | |
All* | Total formula weight | 122700.9 |